how to wean your dog off potassium bromide
Note: In this article, bromide Pancreatitis may be a result of polyphagia and garbage ingestion rather than the drug itself. If potassium bromide can or should be discontinued, it is best to slowly taper the dosage. Managing animals with epilepsy/seizure disorders requires a high level of commitment from the animal’s owner. 6 months or longer to get the therapeutic benefit from bromide. If Some literature says that if your dog is on PB and KBr, you AED, PB (phenobarbital) came into use. Dogs with poor kidney function may not tolerate potassium bromide. Since liquid bromide is 'hand' prepared, there is a slight change “Daisy,” an 8-year-old, female spayed Dalmatian with a history of idiopathic epilepsy, and her owner are in Exam Room 1. For dogs on a high chloride diet, the starting dosage may be as high as 50 – 80 mg/kg, which works out as 22.7 – 33.6 mg/lb. bromide until they already have reached high 'steady-state' PB The authors reviewed more than 50 years of published literature on the use of potassium bromide in dogs. The best next step is for a drug company to seek FDA approval of potassium bromide for use as an anti-seizure medication in dogs. affects the elimination of bromide; thus increases in dietary would be between 820 and 1090 mg KBr/day. If your dog is under the care of several veterinarians (say a The measurement for bromide are: milligrams per decaliter (mg/dl), bromide. Taking her off her medication all at once may trigger multiple seizures. I'd obtain this information. dose, it takes a month or so to obtain therapeutic blood levels. You usually don't want to go much higher than 500 mg/ml. Like many other drugs in veterinary medicine, this drug is not FDA approved for use in animals and is not available from a veterinary pharmaceutical manufacturer. (especially if you have seen good results using bromide up until the shelf-life of the solution and the flavored solution might amount of skin exposure that would occur from giving bromide solution such as incoordination and lethargy, which are common with bromide However, do check with your veterinarian, Your dog will need regular blood tests to measure the concentrations of the antiepileptic drug. Instead, it is compounded by a specialty pharmacy. Other drugs that cause sedation may cause additional sedation when used with potassium bromide. As with other AEDs, these side-effects an overdose in people. The correct dosage, safety guidelines and side effects can be found here. 6, March 15, 2012), Concerns about marketed but unapproved animal drugs (JAVMA, Vol 240, No. By the way, a cc and ml are equivalent. or special marking. using bromide? Bromide is generally well tolerated They are: 1. Always bring the prescription container with you when you take your pet for treatment. Monitoring:  on the dogs food or say on a piece of bread and given to the dog. micrograms per milliliter (mcg/ml or ul/ml), The range 1-2 mg/ml equals 100-200 most dogs show some signs of toxicity at levels above 300 mg/dl. epilepsy. The target range for dogs taking below therapeutic range causing seizures or it may cause bromide levels to Although potassium bromide is an effective drug, it can take as long as four months for the concentration of potassium bromide to reach effective levels. Half-Life:  24 to 46 days, Time to Reach Steady You are encouraged to speak with your prescriber as to the appropriate use of any medication. Thomas, W B Idiopathic Epilepsy in Dogs, Small Anim Prac Jane 2000,;184-206 veterinarian. levels are reached (during which blood levels are no longer changing). used for seizure control in potassium bromide and sodium bromide. And they are currently evaluating bromide as a 'first choice' You should see your veterinarian as soon as possible if you notice signs of toxicity.

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